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    One of the founders of Kraftwerk, the 1970s German electronic dance music pioneers, Florian Schneider, has died of cancer at 73. Kraftwerk was kind of like Led Zeppelin if the Germans had won the War: Kraftwerk was an extremely infrastructure-oriented band: I never really got Kraftwerk until Devo came along in the later 1970ss From...
  • OT: Father and son arrested for the shooting in Brunswick, GA. What interests me is the likelihood of Arbery actually being a burglar. The distance from his house and the place of the shooting is difficult if not impossible to find in mainstream sources. 4chan says it’s 11 miles yet news articles are saying 2 miles. My hunch says 11 is closer to the truth based solely on the simple fact of it being difficult information to obtain.

  • From the New York Post: This idea came out of data-mining in China where it was noticed that poor peasants who had their heartburn treated with non-prescription Pepcid-like pills died only half as much as rich folk with heartburn who had a prescription for the state-of-the-art pharmaeutical. Exactly how much is hydroxychloroquine being used anyway?...
  • @Anon
    Pepcid also contains magnesium. Here's a study that says rats can get an exaggerated immune response if they're magnesium deficient.

    https://www.sciencedirect.com/science/article/abs/pii/S002432059800455X

    Here's another paper on magnesium and cytokine response in rats. "During the progression of Mg deficiency in a rodent model, we have observed dramatic increases in serum levels of inflammatory cytokines."

    https://journals.physiology.org/doi/abs/10.1152/ajpregu.1992.263.3.r734

    I think it's the magnesium in the Pepcid that's helping prevent the cytokine storms of Covid-19, not just the histamine 2 blocker.

    Magnesium is known to make Vitamin D more bioactive, and you need Vitamin D for proper immune system function.

    Pill up, people pill up. Magnesium is readily available. I've been taking a magnesium supplement for the past decade, and I've only been sick once in that time that I can recall.

    Replies: @Aj7575, @HA

    What is your dose?

    Also, many people report long term supplementation as giving them brain fog.

    • Replies: @Mr. Anon
    @Aj7575


    Also, many people report long term supplementation as giving them brain fog.
     
    Long term supplementation generally, or just with magnesium?
  • Hydroxychloroquine hasn't worked well in studies for people on death's doorstep from coronavirus, but most of the optimism about this old drug instead has always been about its potential in earlier phases. From Il Tempo via Google Translate: Coronavirus, revealed how it works: that's why hydroxychloroquine could work by Peter D'Angelo APRIL 28, 2020 ......
  • @Travis
    Chloroquine was discovered to be a potent inhibitor of SARS coronavirus infection and spread back in 2004. Hydroxychloroquine (HCQ) has similar anti-viral properties. This has been known for decades. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1232869/

    https://www.sciencedirect.com/science/article/abs/pii/S1043466614002427
    HCQ an autophagosome-lysosome fusion inhibitor broadly used in autophagy pathway research. Mechanistic study suggested that HCQ activated the innate immune signaling pathways. These results reveal an emerging role of HCQ activating the host innate immunity against virus infection.

    unfortunately these drugs are in short supply and not available at the pharmacies. I have been able to obtain several cases of tonic water which contains quinine. It has similar antiviral properties and works as a zinc ionophore to get zinc into the cells where it disrupts viral replication.

    Chloroquine is an amine acidotropic form of quinine and emerged approximately 70 years ago as an effective substitute for natural quinine. Chloroquine and hydroxychloroquine belong to the same molecular family. The Cuomo family treated themselves with quinine when they all came down with the Wahu flu. Be prepared and stock up on zinc, tonic water and make sure you get enough vitamin D.

    Replies: @Aj7575, @Philip Owen, @Currier House

    Thanks.

  • A commenter provides an overview of the news: Dear Steve, What follows are the opinions of one observer — a non-clinician, at that — about the pandemic we’re experiencing, gleaned almost entirely from open-source material. This is a snapshot; people who are paying close attention will already know most of what I relate. First, the...
  • @vhrm

    * When infectious virus particles rather than viral RNA are measured, the drop is even more dramatic. If substantiated, this means that after 5 days of hchlor/az therapy, patients are much less contagious. (This is new: to my knowledge, Raoult is the only one routinely performing the cumbersome assay of infectious viruses on clinical samples in a study like this.)
    ...
    * Hchlor/az is unhelpful (or marginally helpful) for critically ill patients.

     

    A possibly similar process that some of you may have the misfortune of being familiar with is a cold sore outbreak on your lips (aka herpes simplex virus 1). If you hit it early with Abreva it goes away quickly and does no damage. The longer it takes to catch it the more damage gets done and after about 2 or 3 days it's too late to intervene and you have to ride out the whole thing.
    Of course, damaged lip cells vs damaged lung cells has a VERY different impact on the rest of the body, but the similarity i'm pointing to is this issue of tissue damage that still is there even after the virus replication is stopped or slowed if you don't stop/slow it soon enough.

    Since this got long and boring here's my first MORE.


    So with cold sore flares the virus that normally lives in some nerves near the mouth with no symptoms starts replicating near the skin after some trigger (illness, sunburn, stress, chapped lips). It then follows the same pattern which is in my observation tingle/swelling -> hard clear blisters -> soft cloudy merged blisters -> injured skin -> healing. Takes a good 2.5 - 3 weeks for me anyway.

    The actual damage is done up front with those blisters. That's when the virus is replicating hard core in your cells and blowing them up. Then the immune system seems to get that under control, but you're still left with an injured lip from those blown up cells and it takes a while for the skin to heal even with no additional damage being done.

    From a treatment point of view, if you notice the thing coming on and hit it with Abreva (doconasol) starting early and often (or possibly with some prescription-in-the-US-but-otc-in-EU antivirals), you nip it in the bud and the whole thing stops overnight often with no visible damage.

    If you hit it in the first several days it still limits the damage some and the eruption is smaller than it would have been, but there's still damage that has to heal. After the first several days though, it doesn't really do anything because all the damage's already been done.

    An interesting thing i've noticed is that the clinical studies of doconasol make it sound like it's barely effective: e.g. reduces duration of symptoms from 5 days to 4 days (https://www.ncbi.nlm.nih.gov/pubmed/11464183 )

    But if you read the reviews on amazon many of them sound a lot like what i described above (https://smile.amazon.com/Abreva-Docosanol-Treatment-Approved-Blister/dp/B071K8PFHG/ )

    So this also captures that some people clearly have a worse natural course than others (e.g in the study the mean resolution was 5 days, but clearly for many it's longer than that ) AND the fact that you have to stop the virus early before it damages a bunch of cells.

    Replies: @Chief Seattle, @JerseyJeffersonian, @Aj7575

    Your anecdote about abreva mirrors what people say about zinc lozenges and the common cold – mainly that it is effective only if you treat it right away.

    • Replies: @Anon
    @Aj7575

    Well, of course. Your lungs can't suck on a zinc lozenge.

  • Richard Lynn - RACE DIFFERENCES IN PSYCHOPATHIC PERSONALITY (2019) Rating: 5/5 TLDR: Global survey of racial differences in psychopathic personality confirms the standard Rushtonian pattern of Negroids < Caucasoids < Mongoloids on the r/K life history scale. You can access all of my latest book, film, and video game reviews at this link, as well...
  • @Mr. XYZ

    Over the next twelve chapters, Lynn carries out an exhaustive survey of racial differences in psychopathic personality around the world. The regions/groups covered include: The US; Canada; Europe; Sub-Saharan Africa; South Asia; The Caribbean; Australia; New Zealand; Pacific Islanders; the Inuit; Latin America. There is also one chapter that analyzes international differences. On this basis, a hierarchy of racial differences that matches J. Philippe Rushton’s classic r/K schema is revealed: Northeast Asians < Europeans < Hispanics & South Asians < Native Americans < Maori < Sub-Saharan Africans < Aborigines. Accounting for psychopathic personality in addition to intelligence provides a much closer explanation of racial differences in crime rates than IQ just by itself.
     
    What about Middle Easterners and North Africans? It would be interesting to compare their scores with those of Europeans.

    I also wonder if there are differences among different groups of Europeans in regards to this.

    In the last chapter, Richard Lynn extends Cold Winters Theory to explain the racial hierarchy in in psychopathic personality. First, colder climes necessitated stronger male-female pair bonding, to ensure that children remained cared for. Second, they encouraged selection for gratification delayal, due to the necessity of storing food over the cold winter months (whereas in the tropics, plant and insect food sources are available year round, which diminishes the utility of long-term planning). Third, they selected for the ability to maintain cooperative social relations due to the greater emphasis on big game hunting. Fourth, they selected for a reduction of sexual promiscuity, since hunters who are gone for days at a time need some reassurance that the guys who stayed behind aren’t banging their partners back at the base camp. These selective forces acted to different extents on the various races of Man, with Negroids in the tropics less affected than Caucasoids in the temperate regions, who were in turn less affected than Mongoloids in the taiga.
     
    Are southern Chinese and Vietnamese different from northern Chinese in regards to these traits? After all, I seem to recall that James Flynn previously used the example of southern Chinese to argue against the Cold Winters Theory.

    Replies: @Nodwink, @Aj7575

    I remember reading on Unz that southern Chinese are northern Chinese that displaced and sinicized the original inhabitants of South China.

  • Since the murder of Barnard College freshman Tessa Majors on December 11, the Main Stream Media have been up to their usual tricks. As with the Knoxville Horror and so many other crimes, they have, yet again, downplayed or suppressed outright the racial angle and the savagery of the killers, who mutilated the 18-year-old beauty’s...
  • @Beefcake the Mighty
    @Aj7575

    Reasonable points, but you’re leaving out Knox’s known record of promiscuity.

    Replies: @Aj7575, @Alden

    It’s a tame record – 7 men at 20 years old. But yes it does have some weight because you CAN judge someone by their promiscuity – I’ll give you that.

    The sexual deviant angle always seemed fantastical to me. It’s a huge leap from Promiscuous to fucking a semi homeless poor ugly stranger. And what about Raffaele Sollecito? Are we to believe that he was down for that – tired of slaying hot white women and instead wants to get into cuck play with a black bum? Look him up. Women are status seeking while men are beauty seeking. So it’s beyond me why she would fuck Guede, let alone her chad boyfriend. It’s such a wild conclusion.

  • @Pecosbill
    @Sean

    Italy tried Knox three times for participating in Meredith Kercher's (Queen's subject) murder. Twice they convicted her and once acquitted. When the last conviction worked its way to the Italian Supreme Court they dismissed the case against her and her boyfriend Sollecito. Nevertheless the court said the evidence showed Knox present during the murder since cops found Meredith's water diluted blood washed off in the adjacent bathroom mixed with Knox's exfoliated DNA.

    The court ruled that if Knox was at the murder scene then so was Sollecito. His pressure DNA was on Meredith's cut off bra clasp. There's so much evidence direct and circumstantial that likely any Crown Court or State's Court would convict. In Texas she'd be on death row since Meredith's murder occurred during the commission of other felonies, bodily and sexual assault. Prosecutors would consider the murder committed under special circumstances, primary torture with knife pricks to cause pain and suffering, crushing Meredith's throat when she screamed for help, and letting her drown in her own blood which took several minutes all the while she knew she was dying.

    Courts ruled Meredith had multiple attackers, Guede was one and Knox and Sollecito were the other two. Two knives were involved in the attack, a pocket knife and a kitchen knife. Meredith was a fit young woman and athletic yet she had no defensive wounds on her hands and arms meaning her arms were held. Guede, by himself perhaps could have carried out the rape, but Meredith would certainly have defensive wounds and likely would have survived.

    Knox rendered her statement that she was at the murder scene after only a short time being interviewed and after she learned that Sollecito blew her cover story. Anyway, the court disallowed that 'confession' since cops did not read her rights to remain silent. She pointed the guilty finger at a man she worked for at a bar, African, Patrick Lumumba as the one who raped and killed Meredith while she, Knox, was in the kitchen of the little cottage. Cops arrested Lumumba, and Knox, knowing she lied, let him loiter in jail for about two weeks. She has never recanted that lie and Patrick sued and was awarded some fifty thousands of Euros. Knox is a convicted felon as all courts let her conviction stand on knowingly making a false charge in a murder case.

    Knox was a pretty girl at the time of the murder but so was Meredith. The latter being one an old boy might considered taking home to mama, the former to a Motel-6.

    The last court to convict Knox had the problem of getting her back from the US where she went when the second trial freed her. Since Knox was tied into a drug ring via a drug dealer she was screwing for cocaine, Italians planned to use the drug traffickers section of a treaty signed with the US for cooperation in these matters. Knox's drug dealer served time in an Italian prison for drug offenses. Cops found him via his phone number discovered on Knox's mobile.

    Replies: @Aj7575

    Please reconsider the Knox case. Bayesian probability requires us to consider priors. Her dodgy behavior and lies after police custody are only part of the equation, you must consider prior probabilities before new evidence.

    She’s a white woman, which already tells us a lot because men are over represented 5 to 1 in the murdering game. Next what kind of white women was she? Your average 100 iq gal with prospects in retail? Far from that, she went to a competitive school and is from a family with enough money to send her abroad. And she had the brains to actually learn Italian. She’s good looking and so is her what looks like N. Italian boyfriend. Finally she’s being accuse of being apart of a multi assailant murder, you are now dealing with tiny probabilities now.

    She’s innocent for the same reason a Brad Miller is a better candidate for a job than DaQuan Jones with out looking at a resume. Probability has predictive validity.

    Now let’s look at the evidence that’s supposed updated our priors. Her skin cells in a bloody sink that was a shared space is not even remotely incriminating. She did lie about the bar owner, but it was a false confession under pressure. So she picked a black dude. She’s already freaked out that her boyfriend supposedly game her up and she panicked.

    Occam’s razor – what’s more likely, a low impulse ugly black criminal raped and killed Meredith(proven) or a low impulse ugly black criminal raped and killed Meredith AND also had help from a rich, beautiful, at least 115 iq+ white woman AND her handsome boyfriend?

    Unless the evidence is absolutely damning you can’t overcome the prior probabilities.

    • Agree: Alden
    • Replies: @Beefcake the Mighty
    @Aj7575

    Reasonable points, but you’re leaving out Knox’s known record of promiscuity.

    Replies: @Aj7575, @Alden

  • @Beefcake the Mighty
    @Aj7575

    He’s a raging homo, as indicated by his frequent comments on male genitalia (which he’s doubtless experienced front and back, if you catch my drift). However, I agree with you that he’s probably right about the CP5. They’re animals who should be removed from civilized society (and it says volumes about the liberals who defend them), but their role in that crime appears to be opportunistic at most.

    Replies: @Aj7575, @Alden

    I only think he’s partially right about CP5. They might not have penetrated her but are none the less guilty of creating the circumstances leading to her rape. No doubt some if not all were there before or during.

    • Replies: @Beefcake the Mighty
    @Aj7575

    I agree, they were peripherally involved at a minimum and deserved harsh punishment for that and other crimes. Likely the NYC police (no kind of heroes BTW) were under intense political and bureaucratic pressures to resolve the case and were handed some very likely suspects despite lacking an airtight case. Not very public-minded police work, but not the greatest travesty of justice either. Also it’s worth noting that Reyes’ confession should not be overstated: it’s completely self-serving as it was past the statute of limitations (hence no risk to him), and he surely knew it would trigger a lawsuit by the 5 against the city. So Sean is not simply being contrary here, he’s trolling. He still has yet to address what societal cost was incurred here by the flawed convictions (maybe he’s too busy playing hide the baloney with his boyfriend).

    Replies: @David In TN, @Sean

  • @Ron Unz
    @Nicholas Stix


    Was using Knox your own invention, or is that now part of the standard bag of CP5 Hoax lies?

    You fantasize that I am obliged to take your lies seriously.

    Initially, I ignored your lies, but you clogged up the thread with such a quantity of lie-filled comments that I became concerned that people unfamiliar with the Jogger Case might be misled by you.
     
    Even among all the eccentric commenters on this website, this "Sean" character is really a strange one, maybe some sort of psychopath. But his volume of comments is so enormous---almost 1.5M words over the years---and he spends so much time on this website, perhaps 50+ hours per month, that it's also quite possible that he's some sort of paid troll.

    Anyway, his endless clutter is the sort of thing I'm hoping to sharply reduce with my new commenter restrictions.

    Replies: @Aj7575

    I spend 50+ hours a month on Unz.com while just commuting alone and I consider myself merely a lurker, I might recognize a handful of commenters. Not knowing much else about Sean his posts in this thread seem reasonable and nuanced. He seems accept HBD. He’s just being contrarian on a topic that seems to get lopsided support.

    Anybody want to let me know what’s so bad about this Sean guy anyway?

    • Replies: @Beefcake the Mighty
    @Aj7575

    He’s a raging homo, as indicated by his frequent comments on male genitalia (which he’s doubtless experienced front and back, if you catch my drift). However, I agree with you that he’s probably right about the CP5. They’re animals who should be removed from civilized society (and it says volumes about the liberals who defend them), but their role in that crime appears to be opportunistic at most.

    Replies: @Aj7575, @Alden

    , @Beefcake the Mighty
    @Aj7575

    And I should add: his frequent willingness to introduce irrelevant points (like his spurious defense of Amanda Knox) is one of the reasons most people here find him highly suspicious.

    Replies: @Sean

    , @Sean
    @Aj7575

    Yes I am a contrarian, maybe I have been overdoing it lately. I was also a bit offensive to our host on another thread.

    , @Alden
    @Aj7575

    He claims that 5 black and brown teens didn’t beat aWhite woman almost to death and are completely innocent of even touching her.

    Her name is Patricia Meili. 12 days in a coma, years of surgery and therapy, they were rightfully convicted.

    Being a woman LEO I don’t like his numerous posts that the defendants in one of the most egregious 5 black& browns on 1 White woman attacks are innocent.

    Sean tried to conflate the recent armed robbery and murder of White woman Tessa Majors by 3 useless black 8th graders with the Patricia Melli case and proclaim the 3 8th graders are as innocent as he claims the 5 black&brown attackers of Patricia Meili are innocent.

    He keeps posting and posting the same liberal idea that blacks and browns either are innocent or justified in hyena pack attacks on a lone White woman.

  • Writing about intelligence is splendid fun if you like watching dogfights among towering vanities. (This assumes that vanities can tower, though I’m not sure how dogs come into it.) On one side you have the politically correct protectors of Appropriate Values. These secretly believe that blacks are less intelligent than whites and live in terror...
  • @Adrian
    @Pincher Martin

    Quasi-religious feelings? That is new to me. He has been chided for his alleged over-reliance on some specific material factors - not for religious feelings.

    I must confess that I cannot understand how someone who claims to have read most of his books (some of them repeatedly) could come up with such an uninformed comment on Papuans as this:


    Well, I hate to be the one to break it to you, but the opportunity has been provided numerous times to these fellows. The lessons never seem to take.
     
    I think that either Voltaire or Mencken, with whom you seemed to compare yourself in your last post, would have read Diamond with greater profit.

    Replies: @Aj7575

    This was a very well done critical review of the book.

  • From The Guardian: Who's the daddy? Paternity mixed up in cities, study finds Illegitimacy more likely over past 500 years among urban poor, say geneticists Ian Sample Science editor Thu 14 Nov 2019 12.15 The Romans had a phrase that summed it up nicely: mater semper certa est, pater semper incertus est. The mother is...
  • I wonder what analysis on East Asian cultures would yield. The Japanese are famous for male adult adoptions when there is no suitable heir. Similarly a Chinese family with no sons would “adopt” an infant or baby from a poor family.

  • Here's a new paper in Nature on inbreeding depression: it's bad. Don't marry your first cousin. (Here's my 2003 article "Cousin Marriage Conundrum.") A sample size of > 1.4 million ... James Lee et al's 2018 GWAS on educational attainment was the first genetic study I can remember with a 7 digit sample size. Now...
  • So marriage within your race is the Goldilocks range? Too interbred bad and not interbred enough also bad.

    • Agree: Rosie
    • Replies: @black sea
    @Aj7575

    I think Edward Dutton argues that marriage with someone at the level of eighth-cousin kinship is the ideal between not too familiar and not too exotic.

    Replies: @RadicalCenter

    , @Anonymous
    @Aj7575


    So marriage within your race is the Goldilocks range? Too interbred bad and not interbred enough also bad.
     
    Pretty much.

    It's just common sense. No one needs aboriginal or congoid genetics in the modern world.