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From Fox News:
Stanford uses CRISPR to correct sickle cell, human trials planned
Published November 08, 2016 Reuters
CHICAGO – Scientists at Stanford University School of Medicine have used the CRISPR gene editing tool to repair the gene that causes sickle cell disease in stem cells from diseased patients, paving the way for a potential cure for the disease, which affects up to 5 million people globally.
“What we’ve finally shown is that we can do it. It’s not just on the chalkboard,” said Dr. Matthew Porteus, senior author of the study published in the journal Nature.
With the study, and unpublished findings from his lab, Porteus believes his team has amassed enough proof to start planning the first human clinical trial using the powerful CRISPR-Cas9 gene editing system to correct the genetic mutation that causes sickle cell disease.
From the New York Times:
Human Gene Editing Receives Science Panel’s Support
By AMY HARMON FEB. 14, 2017
An influential science advisory group formed by the National Academy of Sciences and the National Academy of Medicine on Tuesday lent its support to a once-unthinkable proposition: clinical efforts to engineer humans with inheritable genetic traits.
In a report laden with caveats and notes of caution, the group endorsed the alteration of human eggs, sperm and embryos — but only to prevent babies from being born with genes known to cause serious diseases and disability, only when no “reasonable alternative” exists, and only when a plan is in place to track the effects of the procedure through multiple generations.
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