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Kalash

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Kalash women in traditional clothing

Kalash women in traditional clothing

Ayub Khan with a German general

Ayub Khan with a German general

If you read Nell Irvin Painter’s The History of White People you will learn that the white race is a social construction of relatively recent vintage. When I read her work in 2011 I was a touch annoyed by it, because a lot of interesting empirical data was shoehorned into her thesis and preferences. In relation to her putative topic, she wasn’t a big fan (I don’t doubt that Painter likes white people as humans, but she obviously thinks that the invention of the white race was not a good thing). I have serious reservations and objections to these sorts of Manichaean frameworks. And yet over the last few years I have come to a very different but new perspective: I believe white people emerged biologically only in the past 5,000 years, on the edge of history and prehistory. I think a plain reading of the race concept in biology is entirely defensible so long as you integrate population thinking. But, human races are not primordial. They aren’t even Pleistocene.

Book-cover-UK This brings us to the Kalash of Pakistan. They are pagans who live in the fastness of the Chitral. Their cousins on the other side of the border, in Afghanistan, are the Nuristanis, who were foricbly converted to Islam in the last decade of the 19th century. The Man Who Would be King takes place among the Nuristanis, who were then termed Kafirs. It was written in 1888, before the conversion to Islam. The Kalash were in British India, so spared from conversion. It seems unlikely that they will persist beyond this generation due to the social-political milieu of modern Pakistan, where religious toleration only exists for economic elites who can withdraw into their own private world. It was this context which drove Gerard Russsell to include the Kalash in his book Heirs to Forgotten Kingdoms: Journeys Into the Disappearing Religions of the Middle East. The Kalash are not Middle Eastern, and are very different from various heterodox groups of the Middle East (who often have connections to the astral religion of Late Antiquity), but there is an urgency in recording their culture before it disappears.

Another major salient aspect of the Kalash is that they are mostly white. That is, if you took a Kalash man and dressed him in jeans and a baseball cape wouldn’t think twice if you saw him in a country music video. Let me quote from Man Who Would be King:

“‘In another six months,’ says Dravot, ‘we’ll hold another Communication and see how you are working.’ Then he asks them about their villages, and learns that they was fighting one against the other and were fair sick and tired of it. And when they wasn’t doing that they was fighting with the Mohammedans. ‘You can fight those when they come into our country,’ says Dravot. ‘Tell off every tenth man of your tribes for a Frontier guard, and send two hundred at a time to this valley to be drilled. Nobody is going to be shot or speared any more so long as he does well, and I know that you won’t cheat me because you’re white people — sons of Alexander — and not like common, black Mohammedans. You are my people and by God,’ says he, running off into English at the end — ‘I’ll make a damned fine Nation of you, or I’ll die in the making!’

And later:

… Dravot gives out that him and me were gods and sons of Alexander, and Past Grand-Masters in the Craft, and was come to make Kafiristan a country where every man should eat in peace and drink in quiet, and specially obey us. Then the Chiefs come round to shake hands, and they was so hairy and white and fair it was just shaking hands with old friends. We gave them names according as they was like men we had known in India — Billy Fish, Holly Dilworth, Pikky Kergan that was Bazar-master when I was at Mhow, and so on, and so on.

The genetics on the pigmentation loci make it clear why the Kalash are so fair. They are fixed at SLC24A5 for the derived variant. In fact their pigmentation genes are rather similar in allele frequency distribution to Sardinians (check SLC45A2 and OCA2/HERC2). In a European context the Kalash are not notably fair skinned, but a substantial number can clearly pass as white without difficulty because for all practical purposes they are white physically. The observations of Kipling’s narrator in Man Who Would be King holds true today, white Western journalists who need to pretend to be native in Afghanistan take on a Nuristani identity. Even if most Nuristanis and Kalash are not blue eyed and blonde haired, enough are that it is not totally implausible that a fair Northern European could pass as one of them.

Though the Nuristanis and Kalash are at one end of the distribution in South Asia, they’re not total aberrations. Many Pathans, for example, basically look white. Above I posted the photo of Ayub Khan, military dictator of Pakistan in the 1960s. He was an ethnic Pathan. Khan loomed large in my father’s recollection of this period. When he arrived in Pakistan to complete his master’s degree he was surprised that most people were not white like Ayub Khan!

Which brings me to the question, if a subset of people on the Northwest fringes of the Indian subcontinent are physically white, are they then related to the peoples of Europe to an inordinate level? In the 19th century the presumption was they were, insofar as these were “Lost White Races,” with some theorists positing connections between high caste Indians and Europeans as Aryans. These sorts of mental frameworks are not particularly unique to Europeans. I’m mostly finished with The Making of Modern Japan, and the Japanese immediately made an analogy in appearance between the Europeans entering their waters and the Ainu people to their North. And then there is the legend of Alexander. In particular, that the Kalash are descended from the Macedonians and Greeks who marched with Alexander. That in truth they are a lost European tribe. I get questions about this pretty much every three to four months. I always answer in the negative. There is no strong evidence of a specific connection. I’ve even made it into the Wikipedia entry for the Kalash:

Discover Magazine genetics blogger Razib Khan has repeatedly cited information indicating that the Kalash are an Indo-Iranian people with no Macedonian ethnic admixture.[47][48][49] A study by Hellenthal et al. (2014) on the DNA of the Kalash peopl evidence of input from Europe or the Middle East (the researchers could not pin down a precise geographic location) between 990 and 210 BC, a period that overlaps with that of Alexander the Great.[50][51]

Screenshot from 2015-08-08 17:24:22 The paper cited to offer up an opening to the possibility of Kalash connections to the Macedonians comes up frequently. It’s known to me, and though the group associated with it is top notch, and the results are certainly impressive, their interpretations are not bullet proof (and the authors are reasonably tentative). I went back and re-read the Hellenthal et al. paper, and checked out their awesome website where you can repeat their analyses. The screenshot to the left shows the Kalash admixture event. They have Greeks and Bulgarians in their data, but the gene flow is from Northern Europe.

Enough talk though. I have data, and will do some more analyses myself. The preliminaries. I took the Reich lab Haak et al. data set (it’s a subset of this), and yanked out a bunch of populations. Additionally, I took the four Yamnaya samples with the best quality genotypes, and created a data set where all their genotypes are included and those that they are missing are excluded (the –mind option in Plink). What I’m saying here is that the variation in the data set is skewed toward the good SNP calls in the ancient Yamnaya samples. After some more quality control I got down to 85,000 SNPs.

First, here is some PCA….

Rplot10 You can’t see it on the thumbnail, and the colors are confusing if you click it, but the Kalash sit square on the northwest edge of South Asian populations. Exactly where you’d expect them to be if they were indigenous to South Asia, and not European transplants. The earlier genetic markers I talked about were a narrow set related to pigmentation. This is genome-wide, sampled out of the 30 million polymorphisms. If you took the pigmentation related loci, Kalash would probably cluster on the edge of Europe. What this shows is that not all genes are representative of genome-wide patterns. SLC24A5 seems to have been subject to selection within South Asia, in situ.

Next I want to zoom in a bit to make a point. You probably want to click to enlarge, but from the top right to bottom left: Greeks, Lithuanians, Yamnaya, Pathan/Kalash.

Rplot11

You notice in this plot that the Kalash are closer to Lithuanians than Greeks. I think a fair minded person would say that the Kalash look more like Greeks than Lithuanians, that is, they’re brunette whites. But genome-wide data show that they are closer to Lithuanians! This is in line with the results you saw above from the Globetrotter genetic admixture methodology. Kalash affinities in Europe are not with Southern Europeans, but Northern Europeans.

Next, we’ll look at PC 3.

Rplot17 Click the image to see it bigger, what PC 3 in these data map onto is a Papuan (up top) and South Asia (bottom) axis. The Kalash are one of the most South Asian populations on this axis! Don’t make too much of this, as there aren’t any South Indian groups. But, it shows that there is something distinctive about the Kalash which is like many other South Asians, and not like Europeans. Not surprisingly the Iranian samples are somewhat shifted toward the South Asians.

The above plots are a bit cluttered. So let’s look at a subsample. Below is a zoom in. PC 1 separates East Asians (off to the left of the plot, not visible) from Europeans. PC 2 separates Yamnaya from everyone else (they are below the bottom edge). I’ve highlighted a few populations.

Rplot18

You can see that the Lithuanians are the most Yamnaya-shifted population. But the Kalash and other Northwest South Asian groups are Yamnaya shifted as well. Not surprisingly, the Druze and Sardinians are the least Yamnaya shifted. The Greeks are not notably Yamnaya shifted, though they are in comparison to the Sardinians.

Now we’ll run Treemix. The parameters -m = 5 and -k = 500. I ran a bunch of iterations. The plots are below.

KalashOut.10 KalashOut.9 KalashOut.7 KalashOut.8 KalashOut.6 KalashOut.4 KalashOut.5 KalashOut.2 KalashOut.3 KalashOut.1

The Kalash are drifted a lot. So they are a long branch often. But you see that most often they are near the other Northwest South Asians. There is no gene flow parameter from Europe. Though that’s probably a function of the other gene flow events being more much significant. So let’s cut down the data set to the same extent as with the PCA.

KalashNarrowOut10 KalashNarrowOut5 KalashNarrowOut6 KalashNarrowOut7 KalashNarrowOut8 KalashNarrowOut9 KalashNarrowOut1 KalashNarrowOut2 KalashNarrowOut3 KalashNarrowOut4

The Kalash are much closer to Europeans in these plots than some South Asians. But why? Clearly it is partly a function of the positioning and affinities of the Yamnaya. Additionally, the Kalash cluser with the Pathans, and to some extent other Northwest South Asians. Geography is stamped genome-wide.

Let me quote from the supplements of Hellenthal et al.:

The Kalash are a geographically and genetically (39) isolated population that have lived in a remote valley within present-day Pakistan for many centuries (40; 66). In the original (Full) analysis, the Kalash possess our oldest estimated date of most recent admixture, of 600BCE (990-210BCE), between sources best represented today by Germany-Austria (though within a range of potential European-related sources, e.g. represented by Turkey in the CentralAsia analysis; 35%) and the nearby Pathan (65%). Intriguingly, this period overlaps that of Alexander the Great (356-323BCE) whose army, local tradition holds, the Kalash are descended from (40). The history of this group is not known: our analysis suggests a major admixture event from a source related to present-day Western Eurasians, but we cannot identify the geographic origin of this ancient source precisely.

In the “Central Asia” analysis of Note S7.4 (but not in the “full” analysis), a very similar ancient admixture signal (always dated older than 90BCE) is seen in five nearby Pakistan populations: the Makrani, Balochi, and Brahui, and more weakly in the Pathan and Sindhi, but not identified in the most northerly groups. Ancient admixture involving sources related to East Asia is inferred in the easterly Burusho and tentatively (within a second signal) the Kalash. These older events are similar in date to that seen in the Kalash but involve less strongly European-like, and more West Asian like, sources (Figure 4; Figure S18), and pre-date recorded history for the region.

The power to detect the events seems a bit weak. Probably better phasing (they had 425,000 markers and used population-based methods) and sample coverage would help. But I think what they’re seeing here are two migration events. First, one with affinities to northern West Asia, which is the majority of the “Ancestral North Indian” (ANI) signal. It is overwhelming in the south and northeast of the subcontinent. A secondary wave probably relates to the Indo-Aryans. It is substantial in the northwestern regions, and less so as you proceed into the Gangetic plain, and present only among Brahmins and other migrants in southern India. It probably correlates well with lactase persistence. I suspect that the Jatts may actually have substantial ancestry from post-Aryan waves based on genetic results I’ve seen.

Where does this leave us in relation to the Kalash? Why is it that they look so much like European whites when phylogenetically they aren’t much more like European whites than many people around them. A few years ago I discussed Indian genetics with John Hawks, and one objection I had to the idea of a European-affiliated Indo-Aryan migration of any substantial demographic heft is that European pigmentation alleles are so rare in South Asians. I’m particularly thinking of European variations of SLC45A2 and OCA2/HERC2. I now understand that my assumptions were wrong. 4,000 years ago Europeans did not look like Europeans!

First, as outlined in Population genomics of Bronze Age Eurasia, Massive migration from the steppe was a source for Indo-European languages in Europe, and Eight thousand years of natural selection in Europe, the genetic character of Europeans as we understand it is a recent phenomenon. Second, as outlined in Genetic Evidence for Recent Population Mixture in India, the genetic character of South Asians is also a recent phenomenon. In fact, both are of the same period, with the finishing touches probably around ~3,000 to 4,000 years ago.

What does this mean? Well, it could be that the “white” phenotype emerged several times in variously related people. In other words, the similarities between the Kalash and Southern Europeans is due to convergence, not common descent. This is reasonable, since all the best evidence now suggests that in many ways the most ancient Southern European populations, such as Sardinians, are among the most distant from South Asians of the European groups. Of course some of the alleles for pigmentation are common. For example, SLC24A5 has a very explosive haplotype structure with little variation. It’s new across its whole range. There are some suggestions though that it is most diverse in the Middle East. It may have swept across all of Western Eurasia recently. Part of the expansion was demographic no doubt, but, part of it was also selection. So being part of the common network of demes, Southern Europeans and Northwest South Asians drew upon some of the same variation as part of their adaptive response to selection pressures.

200px-DarwinsRadio(1stEd) For skin color the standard explanations are out there. The sun, sexual selection, and changes wrought by agriculture. But can they really explain all these concurrent shifts across Eurasia? In Darwin’s Radio the science fiction author Greg Bear posits a genetic time-bomb within us all introduced by a virus that produces species wide saltation. So Neanderthals turned into modern humans almost immediately. It’s a science fiction story. But what about the idea of a disease which selects strongly for the derived variant of SLC24A5? The change in skin color is just a side effect. In fact in South Asia it’s not optimal, though with clothing and avoiding direct sun during the midday, people can deal with it. Instead of a great white race sweeping across Eurasia, I’m positing a great white plague. And not just for white people. What about the sweep around EDAR, which results in many of the characteristics so distinctive about East Asians. It’s a major development gene, but perhaps it too is a reaction to a disease?

linear-300x300 All these things lead me at a strange place. I think human population structure is a big deal. It’s real, it matters. Genetics, and genetic variation matters. But, I also think that a lot of it isn’t very deep in terms of time. That is, a lot of the genetic variation is mixed and matched of recent vintage. Rather than phylogenetic trees, there are reticulated graphs. But not only is the history of our species’ phylogeny radically conditional on the last 10,000 years, many of the salient physical characteristics are also recent, and seem to be popping up everywhere at the same time. And yet, remember Luke Jostins’ plot which showed parallel increase in encephalization across hominin lineages for millions of years? This may not be the first time that inevitable processes were driving many lineages toward the same end points.

 
• Category: Race/Ethnicity, Science • Tags: Genomics, Kalash 
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ka

Kalash girl

Kalash girl

A new paper in The American Journal of Human Genetics, The Kalash Genetic Isolate: Ancient Divergence, Drift, and Selection, illuminates and obscures the history of this enigmatic people. Some framing is necessary here for why the Kalash are important. The Kalash are a “pagan” people who live in the uplands of Pakistan. By pagan, I mean to say that they preserve the primal religious traditions of a strand of the Indo-Iranian peoples, untouched by Islam, or, later developments which led to “higher religions” which arose directly out of Indo-European religion, Zoroastrianism and Hinduism (Sanatana Dharma). It would perhaps be defensible to depict the Kalash as the pagans of yore, a fierce people unbowed by philosophical monotheism or the quietism which explodes out of aspects of the gita.

902168-M Which brings us to another peculiarity of the Kalash: they are white. By white I do not mean white Europeans. They are not. The genetics is not in dispute, the Kalash are distantly related to the other peoples of South Asia. Some South Asians remind white Europeans (and also white West Asians) of themselves when they look at them face to face. But this tendency is heightened in isolated mountain peoples, such as the people of the Chitral valley. Among the Kalash it is more the norm the exception, ergo, legends of descent from the armies of Alexander the Great. In a previous age this paradox of an exotic and pagan barbarian people whose external appearance was white was utilized in fiction. Rudyard Kipling’s novel The Man Who Would Be King is set among the people of “Kafiristan,” what is today called Nuristan. Eight years after the publication of Kipling’s book the people of this region were forcibly converted to Islam by the king of Afghanistan. Even today if a Westerner wants to “pass” as an Afghan it is mostly plausibly as a Nuristani, because some among these people look to be Western in their outward appearance. The Kalash people were under British rule, and so were shielded from conversion to the religion of peace. Today the Kalash are surrounded by territories infested with Pakistani Taliban. Though protected by the state of Pakistan and vigilant against interlopers, it still seems unlikely that they’ll pass through the next generation unconverted.

ma1The Kalash Genetic Isolate is open access, so I invite you to read it. I saw part of the above figure at ASHG 2014. The important aspect of this paper is that it confirms that the Kalash have a great deal of “shared drift” with MA-1, the canonical individual which represents the ancient North Eurasian people who contribute ~10-20% of the ancestry of Northern Europeans and 30-40% of that of Native Americans (and nearly as much as some Caucasian peoples). Unfortunately the tables don’t show f3 statistics of each population, so we aren’t totally clear which population is which in the ternary graphs. But we can make some guesses. The outlier South Asian group is almost certainly the Sino-Tibetan Sherpa group. The South Asian groups include the Gujarati sample from the 1000 Genomes, as well as HGDP populations such as the Sindhis. The West Asians are Iranians, Palestinians, Turks. etc. if this is correct it seems to depict South Asians as sharing a great deal of drift with MA-1. There is also a second plot which shows that Kalash share a great deal of drift with La Brana, the Mesolithic hunter-gatherer from Spain. In contrast to the result from MA-1 it does not seem that other South Asian groups share this drift. To me this is tentative support for the contention in last year’s Science paper that there was some gene flow from Europe to the Kalash over the past few thousand years.

treeBut I need to end here on a down note. Though a lot of the results in this paper are fine, the interpretation strikes me as totally out of kilter with their own citations! They say:

LD decay showed that the Kalash were the first population to split from the other Central and South Asian cluster around 11,800 (95% CI = 10,600−12,600) years ago. This estimate remained constant even after the addition of an African (YRI) population or when the Kalash were compared with different subsets of non-African populations. The pairwise times of divergence with other Pakistani populations ranged from 8,800 years ago with the Burusho to 12,200 years ago with the Hazara.

Most of the populations and clusters that they are speaking of here did not exist when the divergence has been adduced. The Hazara for example are a compound population which emerged in the last 1,000 years due to the admixture of Mongols upon a Persianate substrate. The Uygurs are similar. The “Central” and “South Asian” population genetic clusters are refications of admixed groups which have emerged in the past ~4,000 years. That is, thousands of years after they purportedly diverged from the Kalash. The problem here is that the authors keep forcing their interpretations into a tree, when population genetic history for humans in the Holocene has not been a tree at all. As outlined in Towards a new history and geography of human genes informed by ancient DNA it is plausible that every major group of humans today (major = numerous) is the product of fusions of branches of the human race which were sharply diverged during the Pleistocene. The genomes of individuals and peoples then represent a complex and reticulated graph of interlaced histories. Reducing them to branching trees obscures rather than illuminates.

The deep divergences being inferred here strike me as likely a function of the fact that the authors do not take into account that South Asian populations are themselves a compound of two very distinct groups. One of these, the “Ancestral South Indians” (ASI) are very diverged from the groups of western Eurasia (and, the “Ancestral North Indians”, the ANI). The peoples to the south and east of the Kalash have much higher fractions of ASI, so the calculation of a divergence that is >10,000 years before the present is simply reflecting the very deep divergence of the ASI ancestry from the West Eurasian heritage of the Kalash (note, it is important to remember that the Kalash also have ASI, but just at lower levels).

Overall, this is an interesting paper. There are notable nuggets in it. For example, phenotypically the Kalash are lactose tolerant, but they lack the common Eurasian variant in totality. That implies that there is another variant in the LCT region unique to the Kalash. This also implies that the Eurasian variant has spread relatively recently into Northwest South Asia, perhaps post-dating the arrival of the Indo-Aryans! But the discussion is marred by the straightjacket of tree-thinking, imported from macroevolutionary contexts into a population genetic one, where it is less useful.

 
• Category: Science • Tags: Kalash 
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It is well known that Alexander the Great invaded the Indus river valley. Coincidentally in the mountains shadowing this region are isolated groups of tribal populations whose physical appearance is at at variance with South Asians. In particular, they are much lighter skinned, and often blonde or blue eyed. Naturally this led to 19th and early 20th century speculation that they were lost white races, perhaps descended from some of the Macedonian soldiers of Alexander. This was partly the basis of the Rudyard Kipling novel The Man Who Would Be King. Naturally over time some of these people themselves have forwarded this idea. In the case of a group such as the Kalash of Pakistan this conjecture is supported by the exotic nature of their religion, which seems to be Indo-European, and similar to Vedic Hinduism, with minimal influence from Islam.

Kalash girl, Credit: Dave Watts

The major problem with this set of theses is that they are wrong. And the reason I bring up this tired old idea is that many people, including Wikipedia apparently, do not know that this is wrong. I’ve had correspondents sincerely bringing up this model, and, I’ve seen it presented by scholars offhand during talks. There are many historical genetic issues which remain mysterious, or tendentious. This is not one of them. There are hundreds of thousands of SNPs of the Kalash and Burusho distributed to the public. If you want to know how these populations stack up genetically, analyze them yourself. I know that they aren’t related to Macedonians because I have plenty of European population data sets, and I have plenty of South Asian ones. The peoples of the hills of Pakistan are clearly part of the continuum of the latter, albeit shifted toward Iranian peoples.

Those seeking further proof, and unable to analyze the data themselves for any reason, can check out my posts on the topic:

- The Kalash in perspective

- Kalash on the human tree

Addendum: It would be nice of someone corrected the appropriate Wikipedia entries.

(Republished from Discover/GNXP by permission of author or representative)
 
• Category: Science • Tags: Anthropology, Human Genetics, Human Genomics, Kalash 
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Prompted by my posts, Dienekes, A teaser on the Kalash:

I am in the middle of a ChromoPainter/fineSTRUCTURE analysis of a broad dataset designed to explore certain mysteries that have often come up in my previous experiments. Barring the unexpected, the analysis should be completed sometime next week.

Below you can see the normalized number of “chunks” donated by various populations to the Kalash….

Here is the bar plot which Dienekes generated (left to right indicates extent of “donation” to the Kalash):

I highlighted the most significant non-South Asian donor. Dienekes states:

Of particular interest is the fact that all West Asian populations appear higher on the donor list than all Northern European ones, which confirms, using a haplotype-based approach, my previous inference that the Ancestral North Indian (ANI) component is related to West Asians.

The main issue I would point out is that “West Asians” are probably a major donor to both South Asians and Northern Europeans. In any case, the Lezgian are a North Caucasian non-Indo-Eurpean population. But this is what came to mind:

Geographical distribution of G:

In Turkey, the southern Caucasus region and Iran, haplogroup G reaches the highest percentage of a regional population worldwide. Among Turkish males 11% of the population is G.[4] In Iran, Haplogroup G reaches 13 to 15% of the population in various parts of the country. While it is found in percentages higher than 10% among the Bakhtiari, Gilaki and Mazandarani, it is closer to 5% among the Iranian Arabs and in some large cities.[25] Among the samples in the YHRD database from the southern Caucasus countries, 29% of the samples from Abazinia, 31% from Georgia, 18% from Azerbaijan and 11% from Armenia appear to be G samples.

In southern Asia, haplogroup G is found in concentrations o f approximately 18%[26] to 20%[27] of Kalash, approximately 16% of Brahui,[27] and approximately 11.5% of sampled Pashtun,[26] but in only about 3% of the general Pakistani population.[26] The many groups in India and Bangla Desh have not been well studied. About 6% of the samples from Sri Lanka and Malaysia were reported as haplogroup G, but none were found in the other coastal lands of the Indian Ocean or Pacific Ocean in Asia.[28]

Otzi the Iceman was G, and G is found in mountains areas of Southern Europe, as well as among groups like Tamil Brahmins. My own hunch is that G came with men who first brought agriculture to Europe. This does not mean that they were among the first agriculturalists in South Asia, but there may be some deep connection to pulses out of the trans-Caucasian region.

As far as my initial assertion that the Kalash are a liminal South Asian population, that seems supported by the high matches to many South Asian groups. But my own contention was more specific: that the Kalash exhibit evidence of admixture with the indigenous people of Southern Eurasia, the “Ancestral South Indians” (ASI), attesting to their deep origins within the subcontinent. This is not necessarily true even if they share a lot of haplotypes with South Asians, because the Kalash and Indians proper may share common donors for “Ancestral North Indians” (ANI). Nevertheless, they seem to have some relationship to the ANI-ASI cline identified by Reich et al. (albeit, possibly more complex than that of the Pathans).

(Republished from Discover/GNXP by permission of author or representative)
 
• Category: Science • Tags: Anthropology, Human Genetics, Kalash 
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A recent paper on Turkish genetics has a tree which illustrates a summary of how the Kalash shake out:

I say summary because this tree takes a lot of information and tries to generate the best fit representation. It does hide some information by the nature of its aggregation of patterns. For example, the position of the Burusho, or Turks, has to do with the fact that both of these have low, but noticeable, levels of East Asian admixture on top of a different base. If you removed this eastern element both groups would come much closer to similar groups. The extreme long branches leading to the Kalash and Mozabites are almost certainly a function of endogamy and inbreeding. Their allele frequencies diverged from nearby populations because of isolation.

But notice the nearby populations of the Kalash. They’re northwest South Asian. In many ways if you removed the drift and endogamy from the Kalash I suspect you’d been left with a group very similar to their Pathan neighbors.

Finally, as many of you know I put a substantial number of comments into ‘spam’ on this weblog. Here’s one related to the Kalash which you didn’t see:

“Because of their light skin and hair both the Kalash and Burusho have inspired claims that they are “lost white tribes.” This is almost certainly false for the Burusho. Aside from their moderate East Asian admixture, they’re not so different from other Pakistanis in their region genetically.”

LOL! You are in such denial! A lot of pseudo-scientific mumbo jumbo to spin a lie. OF COURSE they’re of European descent. Claiming European genes as indigenous makes Arabs, Iranians, Middle Easterners and Indians, like you, sound pathetic and desperate.

Geneticists like you could make BRAD PITT’S genes indigenous to South Asia if you wanted to. Where there’s a will there’s a way.

The interesting thing is that this sort of comment is routinely written by white nationalists, Afrocentrists, Indian nationalists, etc. etc. of Racial romanticism often has as great a difficulty accepting the nature of the human phylogeny as those who would like to elide any substantive differences. The only thing I would note though is that this person posted as “liz” at Amardeep Singh’s blog (email: beautifullydrawn@gmail.com, with an IP that traces to Alfred University) so it might beat false-flag troll.

(Republished from Discover/GNXP by permission of author or representative)
 
• Category: Science • Tags: Anthropology, Genetics, Human Genetics, Kalash 
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Kalashpeople_20100312A few days ago I was listening to an interview with a reporter who was kidnapped in the tribal areas of Pakistan (he eventually escaped). Because he was a Westerner he mentioned offhand that to “pass” as a native for his own safety he had his guides claim he was Nuristani when inquiries were made. The Nuristanis are an isolated group in Afghanistan notable for having relatively fair features. His giveaway to his eventual captors was that his accent was clearly not Nuristani, and master logicians that the Taliban are, the inference was made that he was likely a European pretending to be Nuristani.

I thought about this incident when looking over the supplements yesterday of Reconstructing Indian population history. On page 19 note S2 figure 1 includes the Kalash of Pakistan. These are the unconverted cousins of the Nuristanis who were not forcibly brought into the religion of peace in the late 1800s because their region of the Hindu Kush was under British rule, who naturally imposed their late 19th century European value that populations should not be converted by force to a particular religion (Nuristan means “land of light,” whereas before Afghans called it Kafiristan, “land of the unbelievers”). Despite the fair features of the Kalash, which has given rise to rumors that they are the descendants of Alexander the Great’s soldier s, they cluster with Central and South Asian populations, not Europeans. Like the Ainu of Japan it seems superficial similarities to Europeans, at least in relation to the majority population around them, has resulted in an inordinate expectation of total genome exoticism, when in reality a few particular loci are producing the distinctiveness.

Figure 1 from the 2007 paper, Genetic Evidence for the Convergent Evolution of Light Skin in Europeans and East Asians, brings home the point:


skinfig1

The first panel shows a representation of the genetic distance across the genome. Or at least enough to give you a good sense of the phylogenetic relationships. South Asians and Europeans form a clade, as do Native Americans and East Asians. The subsequent panels show Fst values, between population variance, on five genes known at that time to be implicated in between population skin color differences. Note now much different the trees are from the one generated by a large number of loci. Since then more loci have come out of the woodwork, and the peculiar genetic architecture of pigmentation has been rather well characterized. Though most genetic variance may be found within continental races, pigmentation is quite often the exception to this rule. Most of the variance on these loci can be between the races. On SLC24A5 West Africans and Europeans have nearly 100% between population variance. The allele frequencies are disjoint. This shouldn’t be that surprising, skin color is highly heritable, and we already know that there’s a lot of between population difference. So from that one would infer that there would be a lot of genetic variation.

Our skin is our largest organ, and is extremely important as a visual marker of health, age, and identity. The fact that there is so much salient interpopulation difference matters a great deal in the “folk taxonomy” of our species. When considering the relevance of skin color in our taxonomies I thought back to Jared Diamond’s 1994 piece for Discover, Race Without Color:

Regarding hierarchy, traditional classifications that emphasize skin color face unresolvable ambiguities. Anthropology textbooks often recognize five major races: “whites,” “African blacks,” “Mongoloids,” “aboriginal Australians,” and “Khoisans,” each in turn divided into various numbers of sub-races. But there is no agreement on the number and delineation of the sub-races, or even of the major races. Are all five of the major races equally distinctive? Are Nigerians really less different from Xhosas than aboriginal Australians are from both? Should we recognize 3 or 15 sub-races of Mongoloids? These questions have remained unresolved because skin color and other traditional racial criteria are difficult to formulate mathematically.

16 years on I think we can reasonably answer many of Diamond’s questions with phylogenetic trees such as the one to the left. There are five races in the tree by coincidence, though the Khoisans are with Africans, and the Americas has its own branch. Yes, Nigerians are probably less different from the Xhosas than Aboriginal Australians. And I guess this tree implies closer to 15 “subraces” for “Mongoloids.” And with the rise of skin reflectance measures the trait isn’t that difficult to formulate mathematically actually.

But as for the salient phenotypic characteristics which humans use to classify each other, and which will remain important socially and culturally for the near future, it makes absolutely no sense to minimize the critical importance of skin pigmentation. Humans are a very visual species, and the complexion of our largest organ will always be of particular interest. This sort of phenetic classification is not scientifically rigorous, I don’t want cladists to hunt me down, but, it is not an arbitrary cultural construct. We can’t classify people by HLA profiles because we don’t have conscious access to such information (and the idea that we can “smell” HLA profiles is still unproven). Our innate pattern recognition competencies are such that naturally folk taxonomies will start with complexion, and use other characters to refine our categories. Just because something isn’t scientific doesn’t always mean it’s silly or arbitrary.

Image Credit: Outlook India

Addendum: I just realized that Jared Diamond’s article came out at the same time as The History and Geography of Human Genes. A quick consultation of this seminal work would have cleared up some of his questions.

(Republished from Discover/GNXP by permission of author or representative)
 
• Category: Science • Tags: Anthropology, Genetics, Kalash, Race, Taxonomy 
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Razib Khan
About Razib Khan

"I have degrees in biology and biochemistry, a passion for genetics, history, and philosophy, and shrimp is my favorite food. If you want to know more, see the links at http://www.razib.com"